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Systemic inflammatory responses, as well as superoxide, nitric oxide, and peroxynitrite could impair cardiac CPT1 activity in vivo and in vitro , thus leading to myocardial dysfunction (Eaton et al., 2003)

Permanent opening of the mPTP results in mitochondrial depolarization, inhibition of respiration, cessation of ATP synthesis, mobilization of cytochrome C, and apoptosis 43

In addition, the expression density of specific surface markers (CD) on each cell was indicated as MFI